Bad Bacteria Produce Super Glue

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Streptococcus pyogenes is known as one type of pathogenic bacteria or bad. These bacteria can cause throat infections, which caused the death by flesh eating disease syndrome.

However, through research, Mark Howarth and Dijan Zakeri from the Department of Biochemistry University of Oxford succeeded in proving that these bacteria have benefits.

Mark said, Streptococcus pyogenes is able to produce a protein called FbaB. This protein is able to bring together other proteins with super strong covalent bonds.

"Protein is special because it naturally reacts with itself and form a key," explains Mark.

The ability of these proteins was tested in building a longer protein called SpyCatcher, while the shorter protein called SpyTag.

Researchers trying to unite the two buildings with FbaB protein and then try to separate them again with the atomic force. The trial results were published in the journal PNAS this week.

The results reveal that the two proteins were difficult to separate. When will be separated, even the bond between the protein and the place is broken. Boiling with detergent also could not separate.

"Our system forms a covalent bond very quickly and with high efficiency and effectiveness," said Mark Physorg quoted as saying on Wednesday (22/02/2012).

When SpyCatcher and SpyTag united, direct bond is formed within a few minutes. Ties will also be formed no matter the temperature or the acidity of the protein.

Remarkably, the proteins of pathogenic bacteria are not going to attach other molecules than proteins. So, no need to worry about this super glue stick to the surface of the other fingers.

Looking ahead, the super glue that is naturally derived from these bacteria may help the development of biotechnology and nanotechnology. This glue can be used to build enzymes or other structures in the nanoscale.

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Bad Bacteria Produce Super Glue
Thursday, 23 February 2012

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